Scientists have known for decades that cancer cells use more glucose than healthy cells, feeding the growth of some types of tumors. Now, scientists have identified compounds that delay the formation of tumors in mice, by targeting a key enzyme that governs how cancer cells use glucose and its metabolites.
Researchers report the development of a mouse model of Fukuyama's muscular dystrophy that copies the pathology seen in the human form of the disease.
A recent study brings new insights to an area of ion channel regulation: whether voltage-gated potassium (Kv) channels can be regulated by physiological changes to PIP2.
A new study has investigated how diseases are shared among species of primates with a view to predicting what diseases may emerge in humans in the future. The findings aim to help in the fight against these diseases by enabling scientists to develop treatments before outbreaks occur.
A new study suggests that nicotinamide, more commonly known as vitamin B3, may be able to combat some of the antibiotic-resistance staph infections and "superbugs" that are increasingly common around the world, have killed thousands and can pose a significant threat to public health.
Scientists have developed and characterized a circulating and pH-sensitive liposome containing cisplatin (SpHL-CDDP) aiming to promote the release of cisplatin near the tumor as well as decreasing toxicity. The development of analog drugs and new formulations are current strategies for increasing the effectiveness and safety of cisplatin as an anti-peritoneal carcinomatosis drug.
Lack of sleep is linked to more aggressive breast cancers, according to new findings by physician-scientists.
Nerves in squid skin control the animal's spectrum of shimmering hues -- from red to blue -- as well as their speed of change, biologists have found. The work marks the first time neural control of iridescence in an invertebrate species has been demonstrated.
Researchers have developed a glue mixture that may reduce risks after laser vision correction surgery. Recent studies describe a new protocol involving brinogen, riboavin and ultraviolet light that could improve the safety of the corrective surgery.
Researchers studying interventions for adolescents and young adults with autism have reported that there is insufficient evidence to support findings, good or bad, for the therapies currently used.
The carbon–oxygen (C=O) double bond is an important chemical motif, particularly in compounds called ketones. Chemists expect that substituting the carbon for a heavier atom would produce 'heavy ketones', which are attractive targets to further understanding of chemical bonding and for synthesizing novel molecules. Now, Kohei Tamao at the RIKEN Advanced Science Institute in Wako, Japan, and colleagues have—for the first time—isolated a heavy ketone, where the carbon is replaced by germanium.
The carbon–oxygen (C=O) double bond is an important chemical motif, particularly in compounds called ketones. Chemists expect that substituting the carbon for a heavier atom would produce 'heavy ketones', which are attractive targets to further understanding of chemical bonding and for synthesizing novel molecules. Now, Kohei Tamao at the RIKEN Advanced Science Institute in Wako, Japan, and colleagues have—for the first time—isolated a heavy ketone, where the carbon is replaced by germanium.
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