Human-chimp genetic differences: New insights into why humans are more susceptible to cancer and other diseases

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Ninety-six percent of a chimpanzee's genome is the same as a human's. It's the other 4 percent, and the vast differences, that has intrigued researchers. For instance, why do humans have a high risk of cancer, even though chimps rarely develop the disease? In a new study, scientists have looked at brain samples of each species. They found that differences in certain DNA modifications, called methylation, may contribute to phenotypic changes. The results also hint that DNA methylation plays an important role for some disease-related phenotypes in humans, including cancer and autism.

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